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The .gov means it’s official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely. Share Traditional systems of medicines need more evidence-based studies on both crude drugs and purified phytomolecules. Utilization of natural products as pharmacological tools could lead to a number of new major therapeutically active metabolites. Lead molecules are further screened for their potential in terms of quality control, safety assessments, and studies about molecular pharmacology and their related properties. Identification, and quality and safety evaluation of natural products, is a fundamental requirement of industry and other organizations dealing with natural health products (NHPs). Marker analysis, based on chemo-profiling and development of characteristic fingerprints for individual plants, could help to develop uniform standardization tools. Beside such evaluations of clinical parameters, safety profiles as well as drug-herb and herb-herb interactions are the most important parameters for assessment and promotion. With the steady growth of the NHPs, advanced analytical- and mechanism-based screening should be considered for their promotion and value addition in every way for the betterment of healthcare. Thus, there is an urgent need for the development of international co-ordination to promote and develop NHPs, including their assessment, perspectives, pharmacovigilance, and potential harmonization of regulation, quality control and clinical uses. Mukherjee PK, et al. J Ethnopharmacol. 2017 Feb 2;197:10-24. doi: 10.1016/j.jep.2016.09.024. Epub 2016 Sep 12. J Ethnopharmacol. 2017. PMID: 27633405 Review. Soll RF, et al. Early Hum Dev. 2020 Nov;150:105191. doi: 10.1016/j.earlhumdev.2020.105191. Epub 2020 Sep 12. Early Hum Dev. 2020. PMID: 33036834 Chen L, et al. J Ethnopharmacol. 2020 Jul 15;257:112829. doi: 10.1016/j.jep.2020.112829. Epub 2020 Apr 18. J Ethnopharmacol. 2020. PMID: 32311486 Review. Kumar S, et al. J Ethnopharmacol. 2021 Jul 15;275:114054. doi: 10.1016/j.jep.2021.114054. Epub 2021 Apr 6. J Ethnopharmacol. 2021. PMID: 33831465 Review. Nandy S, et al. J Ethnopharmacol. 2020 May 23;254:112609. doi: 10.1016/j.jep.2020.112609. Epub 2020 Jan 30. J Ethnopharmacol. 2020. PMID: 32007632 Review. Chevinsky J, et al. AJPM Focus. 2023 Nov 8;3(1):100166. doi: 10.1016/j.focus.2023.100166. eCollection 2024 Feb. AJPM Focus. 2023. PMID: 38283577 Free PMC article. No abstract available. Ahad L, et al. Plants (Basel). 2023 Oct 17;12(20):3599. doi: 10.3390/plants12203599. Plants (Basel). 2023. PMID: 37896062 Free PMC article. Bastidas-Bacca MA, et al. Plants (Basel). 2023 Sep 26;12(19):3390. doi: 10.3390/plants12193390. Plants (Basel). 2023. PMID: 37836130 Free PMC article. Sowa I, et al. Antioxidants (Basel). 2023 Sep 1;12(9):1704. doi: 10.3390/antiox12091704. Antioxidants (Basel). 2023. PMID: 37760007 Free PMC article. Zhang B, et al. Int J Mol Sci. 2023 Aug 23;24(17):13129. doi: 10.3390/ijms241713129. Int J Mol Sci. 2023. PMID: 37685936 Free PMC article.