通过研究自然界中抗冻生物体内的抗冻机制，揭示冰晶成核与生长的分子机制，并指导可控冰晶成核及生长的控冰材料的创制，以控冰材料替代传统冻存中毒性成分的使用，并开展其在冷冻保存细胞、组织和器官中的应用研究。

（2） 防覆冰界面材料

研究冰在固体表面生长的分子机制，设计开发超低冰黏附界面材料，解决低温、高湿环境下风电机组、电力输送、极地舰船等的防覆冰问题。

（3） 冷冻组装调控分子聚集

利用冷冻组装策略，精确调控分子组装过程，实现对有机纳米颗粒及多尺度结构功能材料的可控制备；并应用于介观尺度可控有机纳米光催化、生物组织的高分辨成像、骨 / 韧带等组织工程等领域。

2. Janus effect of antifreeze proteins on ice nucleation; Liu K., Wang C. *, Ma J., Shi G., Yao X., Fang H., Song Y., Wang J. * PNAS 2016, 51 , 14739.

3. Distinct ice patterns on solid surfaces with various wettabilities; Liu J., Zhu C., Liu K., Jiang Y., Song Y., Francisco J *., Zeng X. *, Wang J.*, PNAS , 2017, 114, 11285. ( highlighted by Nature )

4. Bioinspired Ice-Binding Materials for Tissue and Organ Cryopreservation; Liu Z.; Zheng, X.; Wang, J. *, J. Am. Chem. Soc. 2022, 144, 5685.

5. Tuning ice nucleation with counterions on polyelectrolyte brush surfaces; He Z. *, Xie W. *, Liu Z., Liu G., Wang Z., Gao Y., Wang J., Science-Advances , 2016, 2 , e160034.

6. Graphene Oxide Restricts Growth and Recrystallization of Ice Crystals ； Geng H., Liu X., Shi G. *, Bai G., Ma J., Chen J., Wu Z., Song Y., Fang H., Wang J. *, Angewandte Chemie-International Edition , 2017, 56, 997.

7. Spontaneous Freezing of Water between 233 and 235 K Is Not Due to Homogeneous Nucleation; Han Xue,Yang Fu,Youhua Lu,Dezhao Hao,Kaiyong Li,Guoying Bai,Zhong-Can Ou-Yang, Jianjun Wang *,and Xin Zhou *, Journal of the American Chemical Society , 2021, 143, 13548.

8. Use of Ion Exchange To Regulate the Heterogeneous Ice Nucleation Efficiency of Mica; Shenglin Jin+ , Yuan Liu+, Malte Deiseroth+, Jie Liu, Ellen H. G. Backus, Hui Li, Han Xue, Lishan Zhao, Xiao Cheng Zeng *, Mischa Bonn *, and Jianjun Wang *, Journal of the American Chemical Society , 2020. 142, 17956.

9. Precise Control Over Kinetics of Molecular Assembly: Production of Particles with Tunable Sizes and Crystalline Forms; Qingrui Fan, Linhai Li , Han Xue , Heng Zhou, Lishan Zhao, Jie Liu, Junqiang Mao, Shuwang Wu, Shizhong Zhang, Chenyang Wu, Xueming Li, Xin Zhou *, and Jianjun Wang * Angew Chem Int Ed Engl ,2020, 59, 15141.

10. Highly efficient solar anti-icing/deicing via a hierarchical structured surface; Chenyang Wu, Hongya Geng, Sicong Tan, Jianyong Lv, Haiqiao Wang *, Zhiyuan He * , Jianjun Wang, Materials Horizons , 2020, 7, 2097.

11. A Freezing-Induced Turn-On Imaging Modality for Real-Time Monitoring of Cancer Cells in Cryosurgery; Zhiyuan He, Pai Liu, Shizhong Zhang, Jie Yan, Mengni Wang, Zhengxu Cai *and Jianjun Wang *, Angewandte Chemie-International Edition , 2019, 58, 3834.

12. Heterogeneous ice nucleation correlates with bulk-like interfacial water, Shuwang Wu,Jinger Zang,Shenglin Jin,Zuowei Wang,Jianping Wang,Yefeng Yao,Zhiyuan He *,and Jianjun Wang *, Science Advances , 2019, 5, 9825.

13. Bioinspired Materials for Controlling Ice Nucleation, Growth, and Recrystallization; He Zhiyuan, Liu, Kai, Wang, Jianjun *, Accounts of Chemical Research, 2018, 51, 1082.

14. Nonionic and Water-Soluble Poly(D/L？serine) as a Promising Biomedical Polymer for Cryopreservation. Yuling Sun *, Jie Liu, Zhibo Li, Jianjun Wang *, and Yanbin Huang *, ACS Appl. Mater. Interfaces . 2021, 13, 18461.

15. All-Day Anti-icing/Deicing Film based on Combined Photo-Electro-Thermal Conversion, Tongtong Hao ； Zhicheng Zhu ； Huige Yang *, Zhiyuan He *, Jianjun Wang *, ACS Appl. Mater. Interfaces , 2021, 13, 44948.

16. Bioinspired L？Proline Oligomers for the Cryopreservation of Oocytes via Controlling Ice Growth; Qingyuan Qin , Lishan Zhao, Zhang Liu, Tao Liu, Jiangxue Qu, Xiaowei Zhang, Rong Li, Liying Yan, Jie Yan *, Shenglin Jin *, Jianjun Wang *, and Jie Qiao, ACS Applied Materials & Interfaces , 2020, 12, 18352.

17. Fabrication of Anti-Icing Surfaces by Short alpha-Helical Peptides; Zhang Yifan, Liu Kai, Li Kaiyong, Gutowski Voytek, Yin Yuan, Wang Jianjun *, ACS Applied Materials & Interfaces , 2018, 10, 1957.

18. Competing Effects between Condensation and Self-Removal of Water Droplets Determine Antifrosting Performance of Superhydrophobic Surfaces; Guanlei Zhao, Guisheng Zou, Wengan Wang, Ruikun Geng, Xiao Yan, Zhiyuan He, Lei Liu *, Xin Zhou, Jainyong Lv *, Jianjun Wang *, ACS Applied Materials & Interfaces , 2020, 12, 7805.

19. Bioinspired Crowding Inhibits Explosive Ice Growth in Antifreeze Protein Solutions; Zhang Liu, Yan Wang, Xia Zheng, Shenglin Jin, Shuo Liu, Zhiyuan He, Jun-Feng Xiang, Jianjun Wang *, Biomacromolecules , 2021, 22, 2614.

20. Ion-Specific Effects on the Growth of Single Ice Crystals; Shizhong Zhang, Chuanbiao Zhang, Shuwang Wu, Xin Zhou, Zhiyuan He *, and Jianjun Wang *, The Journal of Physical Chemistry Letters , 2021, 12, 8726.

主要授权 中国发明及 PCT 专利 ：

(1) 王健君； 金晟琳 ；严杰；乔杰；闫丽盈；李蓉；一种筛选控冰材料的方法；中国发明专利， ZL201910282418 . 9 。

(2) 王健君； 金晟琳 ；严杰；乔杰；闫丽盈；李蓉；一种控冰材料的分子设计方法； 中国 发明专利 ， ZL201910282422.5 。

(3) 王健君； 金晟琳 ；严杰；乔杰；闫丽盈；李蓉 ； 一种氨基酸类冷冻保存液及其制备方法； 中国 发明专利 ， ZL202010172548.X 。

(4) 王健君； 金晟琳 ；严杰；乔杰；闫丽盈；李蓉； 一种冷冻保存液及其制备方法； 中国 发明专利 ， ZL 202010172544.1 。

(5) 王健君； 金晟琳 ；严杰；乔杰；闫丽盈；李蓉 ； 一种无 DMSO 的冷冻保存液及其制备方法； 中国 发明专利 ， ZL202010171866.4 。

(6) 王健君； 金晟琳 ；严杰；乔杰；闫丽盈；李蓉 ； 一种肽类化合物和含有该化合物的冷冻保存液； 中国 发明专利 ， ZL202010171868.3 。

(7) 王健君； 金晟琳 ；严杰；乔杰；闫丽盈；李蓉 ； 一种冷冻保存用解冻液及解冻方法； 中国 发明专利 ， ZL201910282421.0 。

(8) WANG, Jianjun ； JIN, Shenglin ； LV, Jianyong, YAN, Jie ； QIAO, Jie ； YAN, Liying ； LI, Rong ； 一种仿生控冰材料及含有该仿生控冰材料的冷冻保存液 ； PCT 发明专利，俄罗斯国家阶段申请 2021123840/05(049923) 。

2 016 年获化学科学奖教金（创新奖）