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link管理  ›  TCRDV2 x PSMA - Drugs, Indications, Patents - Synapse
https://synapse.patsnap.com/target/1f46a34aff7231128ca4d4a39ed4559c
捣蛋的针织衫
4 月前
Last update 21 Mar 2024

TCRDV2 x PSMA

T cell receptor delta variable 2 x Prostate-specific membrane antigen

Basic Info

Related Targets
TCRDV2 PSMA

Related

1
Drugs associated with TCRDV2 x PSMA
LAVA-1207
Target
PSMA x TCRDV2
Mechanism
PSMA modulators [+2]
Active Org.
LAVA Therapeutics NV LAVA Therapeutics NV
Originator Org.
VU University Medical Center VU University Medical Center
Active Indication
Metastatic castration-resistant prostate cancer
Inactive Indication -
Drug Highest Phase Phase 1/2
First Approval Ctry. / Loc. -
First Approval Date 20 Jan 1800
3
Clinical Trials associated with TCRDV2 x PSMA
EUCTR2021-001789-39-ES / Unknown status Phase 1/2
A Phase 1 and 2a open-label trial to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, immunogenicity, and antitumor activity of LAVA-1207, a PSMA-targeting bispecific ?d-T cell engager, in patients with therapy refractory metastatic castration resistant prostate cancer
NCT05369000 / Recruiting Phase 1/2
Phase 1/2a Open-label Trial to Evaluate the Safety, Tolerability, PK, PD, Immunogenicity, and Antitumor Activity of LAVA-1207, a PSMA-targeting Bispecific γδ-T Cell Engager, in Patients With Therapy Refractory mCRPC
NL-OMON56169 / Recruiting Not Applicable
A Phase 1 and 2a open-label trial to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, immunogenicity, and antitumor activity of LAVA-1207, a PSMA-targeting bispecific γδ-T cell engager, in patients with therapy refractory metastatic castration resistant prostate cancer - LAVA1207-001
100 Clinical Results associated with TCRDV2 x PSMA
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100 Translational Medicine associated with TCRDV2 x PSMA
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0 Patents (Medical) associated with TCRDV2 x PSMA
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